Radioimmunoconjugates has helped identify and treat various tumors by using a combination of antibodies, which selectively localize tumors, and radiometals, to delineate the tumor areas via PET imaging. Currently, I am developing new [64Cu]-labeled radioimmunoconjugates for colorectal cancer as well as novel approaches with fluorescent label immunoconjugates.
Measuring brain flow currently requires an invasive procedure. I am working on a brain imaging project incorporating light plus sound, accomplishing a noninvasive bedside method for monitoring blood flow particularly useful for neuro intensive care. I am honored to be part of the NanoBioNyc program and hope to incorporate nanobiology techniques to my research.
City College of New York
I am interested in understanding how regulation of gene expression during development influences cell fate decisions, particularly in the vertebrate retina. My specific research project focuses on developing new methods to determine which proteins bind to specific DNA sequences interest to drive these developmental differences.
College of Staten Island
My research involves using computational programs such as NAMD, GROMACS and AMBER to perform molecular dynamic simulation of peptide systems. The project that I am focused on is based on simulating six different peptide-based polyelectrolyte systems in order to probe factors which affect their ability to cluster and form coacervates. Currently, coacervates are being studied as a new type of adaptable material and as a drug delivery method so an understanding of the factors behind coacervation is important.
My research interests lie in the convergence of Cryo-Electron Microscopy and new computational methods of analysis. I am working to integrate AI protein structure programs like AlphaFold into the 3D reconstruction of the membrane protein RyR to help uncover its “social” behaviors and mechanics of function.