Mateusz Marianski

Carbohydrates, one of the three important classes of biopolymers, are involved in a range of biological processes: they serve as structural polymer, energy storage, and recognition module in immune system and cell-cell communication. The Marianski group is interested in: (1) understanding how the molecular structure of carbohydrates relates to their function, (2) developing molecular recognition tools to discriminate between oligomeric carbohydrates and (3) untangling complex parameters space that determines a configuration of new glycosidic bonds during a glycosylation reaction. To study these problems, the group employs molecular simulations techniques which involve classical force-force field and ab initio modeling.